Kentucky rushed for 377 yards and three touchdowns Saturday en route to a 35-21 win over Missouri in Columbia. (University of Kentucky)

COLUMBIA – After falling behind Kentucky 21-7 in the first half, the Missouri Tigers took the opening kickoff of the second half Saturday and marched to the 7 yard line, where they faced a third-and-goal.

The Tigers were one play away from getting back in the game, but anybody who has watched this team this season can predict that didn’t happen.

A 1-yard pass brought up fourth down, and Missouri tried a 24-yard field goal, which Tucker McCann missed.

Kentucky took over, turned a 12-play, 80-yard drive into a touchdown and the Tigers were headed to another lopsided loss.

The Wildcats built a 35-7 lead before coasting to a 35-21 win, with two late Missouri touchdowns doing nothing but making the final score more respectable.

The loss was the 10th in a row in the SEC for Missouri and left them 0-4 in the league and 2-6 on the season. It was only the second road win in the conference for Kentucky since 2010.

Once again, the Tigers’ biggest problem was an inability to stop the run. Kentucky gained 377 yards on the ground, 192 on 38 carries by Barry Snell Jr., who scored two touchdowns, and 182 yards on 19 carries by Boom Williams, who scored once.

Coach Barry Odom had vowed to spend more time working with Missouri’s beleaguered defense this week, and in fact took over the play-calling responsibilities for the unit on Saturday, but with no apparent change in results.

“We didn’t tackle well at all,” Odom said. “We need to figure that out. That’s maybe the single most frustrating thing.”

Kentucky, after building its big lead, only attempted two passes in the second half. Their 582 yards of total offense was their highest output in a conference game since Nov. 11, 2006.

It was the fourth consecutive game in which Missouri gave up more than 500 yards, the worst such stretch in school history.

The Tigers did little of offense either until the fourth quarter, getting their two late touchdowns in the final 11 minutes. After rushing for 156 yards and four touchdowns last week, Damarea Crockett was held to 55 yards on 13 carries.

Missouri has now lost its last four games. They play at South Carolina next Saturday.