COLUMBIA – Drew Lock and the Missouri Tigers might have another opponent besides the Wyoming defense to worry about on Saturday.

The weather forecast calls for rain throughout the day on Saturday, which could affect Lock’s ability to throw the football. Kickoff is scheduled for 6 p.m. and the game will be televised by ESPNU.

In the Tigers’ season-opening win over Tennessee-Martin last week, they scored on their six first-half possessions. Lock played just one series into the second half before finishing his day with 289 passing yards, completing 19 of 25 passes, four of them for touchdowns.

Wyoming’s defense, if not the weather, should present a little more of a challenge. The Cowboys led the country with 38 takeaways last season and much of that defense returns this year.

This will be the Cowboys’ third game of the season, having defeated New Mexico State before losing last week to Washington State. That was a one-point gamer, 20-18, before Washington State pulled away with three touchdowns in the fourth quarter.

Wyoming had two takeaways in the game, one interception and a fumble recovery.

Missouri did not commit in turnover last week, the first time that has happened in the Tiger’s season-opener since 2014.

The Wyoming offense might be without the team’s top running back, Nico Evans, who was downgraded from day to day to doubtful for the game because of a rib injury.

This will be the first-ever meeting between Missouri and Wyoming, although Cowboy’s coach Craig Bohl is quite familiar with the Tigers from his career as a player and long-time assistant coach at Nebraska when the schools were Big 12 rivals.