After giving up 43 points to Missouri State in their season opener, South Carolina scored 31 on Saturday to beat the Tigers 31-13. (South Carolina)

It was another rough night for the Missouri Tigers’ defense on Saturday, and this time their offense could not make up for all of their mistakes.

South Carolina scored two touchdowns in a span of 15 seconds in the second quarter and went on to a 31-13 win over Missouri in the Tigers’ SEC opener in Columbia.

Debo Samuel scored on a 97-yard kick return, and after a pass from Drew Lock was intercepted on the first play after the kickoff, Samuel scored again on the next play on a 25-yard run, wiping out a 10-0 Missouri lead which lasted for only 30 seconds.

‘Our margin of error is absolutely zero," Missouri coach Barry Odom said. "If we don't win the turnover margin and play horrific on special teams, we won't have a chance."

The Tigers gave up 43 points to FCS level Missouri State in their season-opening game last week, but their offense, led by a record-setting seven touchdown passes from Lock, was able to roll up 72 points.

That didn’t happen against the Gamecocks, who limited Lock to 14 completions in 32 attempts for 245 yards and intercepted him twice.

Lock didn’t get much help from his receivers, who dropped numerous passes.

"We had dropped balls all over the place," Odom said. "We're not going to give ourselves a chance to win when we play like that. Every game from here on out it's going to be a four-quarter game. We're not ever going to be sitting around at halftime eating hot dogs."

The Tigers’ only touchdown came on a 61-yard pass from Lock to Jason Reese in the second quarter that gave Missouri the 10-0 lead. It was on the ensuing kickoff – which was supposed to go into the endzone for a touchback – that Samuel broke loose for the long return.

Missouri moves back into non-conference play next Saturday, hosting Purdue.