Game Report: Red Sox 5, Cardinals 4

The Cardinals have had more than a few crushing losses this season, but the one they suffered against the Red Sox Wednesday night might be the worst of the year.

Leading 4-2 going to the bottom of the ninth at Fenway Park, the Cardinals gave up three runs in the bottom of the inning, saw closer Trevor Rosenthal have to leave the game after facing only two batters and had manager Mike Matheny ejected before the Red Sox got the walk-off win on a double by Mookie Betts off the Green Monster.

The biggest impact of all those developments could be the status of Rosenthal, who allowed a leadoff homer and then walked the next batter he faced, not throwing a fastball more than 95 miles per hour.

“Something just didn’t look right,” Matheny said after the game.

After Rosenthal departed, Zach Duke got a strikeout before walking a batter. He was relieved by John Brebbia, who got the second out of the inning during a chaotic at-bat by Eduardo Nunez, when Matheny was ejected by home plate umpire Chris Segal, who appeared to call time on his own during a pause in Brebbia’s delivery.

Nunez eventually fouled out, but with both runners on the move on a 3-2 pitch, Betts lined a double off the wall in left that brought home the tying and winning runs. The Cardinals had a play on the winning run, but Yadier Molina could not hold onto the throw to the plate.

It was the Cardinals’ sixth walk-off loss this season.

Here is how the game broke down:

At the plate: Kolten Wong failed twice to get a bunt down with nobody out before he singled in a run, igniting a four-run second inning. Luke Voit, serving as the DH, doubled in a run and Matt Carpenter had an RBI single, but he later was thrown out trying to score from third on a single to center after misreading the play and going back to third to tag up … The Cardinals had only two hits after the third inning, both two-out doubles, by Paul DeJong and Wong … DeJong saw his streak of multi-hit games with one RBI snapped at five.

On the mound: Lance Lynn battled through the first six innings, scattering seven hits and allowed the first two Boston runs, one of which was unearned because of his own throwing error. Lynn has not allowed more than two earned runs in any of his last nine starts dating back to July 4 … Seung Hwan Oh worked a 1-2-3 inning in the seventh and Tyler Lyons had another scoreless outing in the eighth, then turning the 4-2 lead over to Rosenthal for the ninth.

Key stat: Wong was 3-of-4, including two hits off a lefthander, to raise his season average to .310. That ties Tommy Pham, who had two hits, for the team lead.

Worth noting: Molina popped out three times after his leadoff double in the second. Since his grand slam on Aug. 9 after the appearance of the rally cat, Molina is just 2-of-20 … Stephen Piscotty hit his fourth homer in six games for Memphis on Wednesday night. Also in that game, Aledmys Diaz played second base for the first time, Patrick Wisdom hit his 26th homer and Jack Flaherty got the win, allowing two runs in 7 1/3 innings, both scoring in his final inning.

Looking ahead: The Cardinals move on to Pittsburgh on Thursday night to begin a four-game series. Adam Wainwright will start the opener against Jameson Tallion.