The Blues knew they needed a big response on Thursday night after playing one of their worst games of the season two nights earlier.

The response began off the opening faceoff, when Brayden Schenn got into a fight, three seconds into the game, and he didn’t stop there.

Schenn scored a pair of goals, including one in a four-goal second period which carried the Blues to a 6-1 win over the Colorado Avalanche at Scottrade Center.

The only negative note of the night was an upper-body injury to defenseman Joel Edmundson, who left in the first period after blocking a shot. The exact nature of the injury was not disclosed, but coach Mike Yeo said Edmundson would not play on Friday night and that the team will have more information about his status at that time.

Schenn scored the first goal of the game on a power play, his 22nd goal of the season, 8:41 into the first period. The Avalanche tied the game early in the second period after a turnover by Vladimir Sobotka before the Blues exploded for the four goals in a span of 10:44, getting goals from Ivan Barbashev, Schenn, Kyle Brodziak and Alex Pietrangelo.

Paul Stastny completed the scoring with a goal in the third period. Vince Dunn had a career-high three assists for the Blues, who scored six goals in a game for the first time since Dec. 9.

Carter Hutton stopped 23 of 24 shots by the Avalanche, who lost their fourth consecutive game against the Blues.

The win kept the Blues in third place in the Central Division with 69 points, one ahead of the Dallas Stars. They opened up a six-point lead over the Minnesota Wild, currently fifth in the division.

The Blues play in Winnipeg on Friday night, with Jake Allen expected to get the start in goal.